Arrhythmia is a common and frequently occurring disease in heart disease, including atrial tachycardia, atrioventricular nodal reentrant tachycardia, atrioventricular reentrant tachycardia, atrial flutter and other supraventricular tachycardia, pre-shock Syndrome, atrial fibrillation, ventricular premature beats, idiopathic ventricular tachycardia, organic heart disease, ventricular tachycardia and so on.
Because of the different mechanisms of heart disease arrhythmia, in the past because of the lack of means and methods, in the treatment of arrhythmia process is often more difficult. In order to be able to control arrhythmia, patients must be given a variety of antiarrhythmic drugs. As the drug treatment can only be controlled to a certain extent, arrhythmia, treatment of arrhythmia can only be maintained by drugs for a long time. Once the drug fails or is discontinued, arrhythmia may occur again. Antiarrhythmic drugs have limited efficacy, side effects, long-term control of arrhythmia attacks less drugs, and long-term high cost of medication. Some large clinical trials have also confirmed that some patients with organic heart disease long-term use of antiarrhythmic drugs, although the patient's arrhythmia can have varying degrees of control, but its side effects and mortality also increased.
Cardiac catheter ablation therapy for rapid arrhythmia has developed into a very mature treatment for the common paroxysmal supraventricular tachycardia, the typical atrial flutter, idiopathic ventricular premature and ventricular tachycardia, the success rate of 90% or more The Cardiac catheter ablation is the introduction of radiofrequency currents into the heart through cardiac catheters, locating at key points of arrhythmia production or maintenance, and then ablation to block reentry loops or eliminate lesions to treat arrhythmias. With the continuous improvement of electrophysiological examination of the heart and catheter ablation techniques continue to mature, more and more types of arrhythmia can be cured.
In recent years, with the application of some new technologies and devices, for many years and drug treatment ineffective or permanent atrial fibrillation, and rheumatic valvular heart disease and other organic heart disease with atrial fibrillation cases, catheter ablation Also achieved good results.
Bilateral ventricular pacing for some patients with heart failure is also a gospel, can improve the quality of life of most patients, reduce the number of hospital deaths due to heart failure, reduce mortality. Implanted pacemaker is the necessary choice for some patients with bradycardia, more in line with the physiological pacing, will be conducive to the recovery of cardiac function, to prevent the occurrence of atrial fibrillation. Coronary angiography, interventional revascularization for patients with coronary heart disease is no longer unfamiliar, the establishment of acute myocardial infarction green channel, emergency intervention surgery for many patients turn the corner. Intra-aortic balloon pump (IBAP) has earned precious recovery time for critically ill patients such as cardiogenic shock, giving them the chance to survive the disease.
In addition, the screening of pathogenic genes is important for the prevention and treatment of hereditary or familial heart disease. Stem cell transplantation and angiogenesis therapy have made many progress in animal experiments, and have good application prospect. Molecular cardiology must not only be in the laboratory to discuss the research project, will eventually bring more clinical practice of new treatment programs.
Second, gene therapy is another new way to treat cardiovascular disease. The main steps include the preparation of the target gene, the introduction of the target gene into the target cell and the expression and regulation of the target gene in the target cell with the appropriate carrier. Cloning technology is increasingly perfect, this new method is likely to make significant changes in the treatment of cardiovascular disease.
Because of the different mechanisms of heart disease arrhythmia, in the past because of the lack of means and methods, in the treatment of arrhythmia process is often more difficult. In order to be able to control arrhythmia, patients must be given a variety of antiarrhythmic drugs. As the drug treatment can only be controlled to a certain extent, arrhythmia, treatment of arrhythmia can only be maintained by drugs for a long time. Once the drug fails or is discontinued, arrhythmia may occur again. Antiarrhythmic drugs have limited efficacy, side effects, long-term control of arrhythmia attacks less drugs, and long-term high cost of medication. Some large clinical trials have also confirmed that some patients with organic heart disease long-term use of antiarrhythmic drugs, although the patient's arrhythmia can have varying degrees of control, but its side effects and mortality also increased.
Cardiac catheter ablation therapy for rapid arrhythmia has developed into a very mature treatment for the common paroxysmal supraventricular tachycardia, the typical atrial flutter, idiopathic ventricular premature and ventricular tachycardia, the success rate of 90% or more The Cardiac catheter ablation is the introduction of radiofrequency currents into the heart through cardiac catheters, locating at key points of arrhythmia production or maintenance, and then ablation to block reentry loops or eliminate lesions to treat arrhythmias. With the continuous improvement of electrophysiological examination of the heart and catheter ablation techniques continue to mature, more and more types of arrhythmia can be cured.
In recent years, with the application of some new technologies and devices, for many years and drug treatment ineffective or permanent atrial fibrillation, and rheumatic valvular heart disease and other organic heart disease with atrial fibrillation cases, catheter ablation Also achieved good results.
In addition, the screening of pathogenic genes is important for the prevention and treatment of hereditary or familial heart disease. Stem cell transplantation and angiogenesis therapy have made many progress in animal experiments, and have good application prospect. Molecular cardiology must not only be in the laboratory to discuss the research project, will eventually bring more clinical practice of new treatment programs.
Second, gene therapy is another new way to treat cardiovascular disease. The main steps include the preparation of the target gene, the introduction of the target gene into the target cell and the expression and regulation of the target gene in the target cell with the appropriate carrier. Cloning technology is increasingly perfect, this new method is likely to make significant changes in the treatment of cardiovascular disease.
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